Growth hormone enhances thymic function in HIV-1–infected adults

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Growth hormone enhances thymic function in HIV-1-infected adults.

Growth hormone (GH) is an underappreciated but important regulator of T cell development that can reverse age-related declines in thymopoiesis in rodents. Here, we report findings of a prospective randomized study examining the effects of GH on the immune system of HIV-1-infected adults. GH treatment was associated with increased thymic mass. In addition, GH treatment enhanced thymic output, as...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2008

ISSN: 0021-9738

DOI: 10.1172/jci32830